Glipizide

Glipizide

Introduction

Glipizide is an oral hypoglycemic medication used primarily in the management of Type 2 Diabetes. It is available as a tablet and is known under the brand name Glucotrol, manufactured by Pfizer Inc.

Overview

Glipizide is classified as a sulfonylurea, a group of medications that work by stimulating insulin secretion from the pancreatic beta cells. It is commonly prescribed in the treatment of Type 2 Diabetes when diet and exercise alone are not sufficient to control blood sugar levels.

Dosage and Administration

Glipizide 2.5mg tablet

The medication is available in a 2.5mg dosage, among others. The starting dose is typically low to minimize the risk of hypoglycemia and then gradually increased based on the patient's response.

Mechanism of Action

Glipizide works by increasing insulin production in the pancreas, which helps lower blood glucose levels. It is part of a broader treatment plan that includes diet, exercise, and possibly other medications.

Side Effects and Precautions

Common side effects of Glipizide include hypoglycemia, weight gain, and gastrointestinal issues. Patients should be aware of the signs of low blood sugar and how to manage them.

Interactions

Glipizide may interact with other medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), other antidiabetic drugs, alcohol, and certain antibiotics. Patients should inform their healthcare provider of all medications they are taking.

See Also

• Diabetes Mellitus Type 2
• Hypoglycemia
• Sulfonylurea

References

1. Pfizer Inc - Glipizide Information 2. National Center for Biotechnology Information - Glipizide in Type 2 Diabetes Management

External Links

• American Diabetes Association
• U.S. Food and Drug Administration - Medication Guides

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