Glucoside
Glucoside
Glucosides are a type of glycoside that are derived from glucose. They are compounds in which a sugar is bound to a non-carbohydrate moiety, typically through a glycosidic bond. Glucosides are widespread in nature and can be found in many plants and some animals.
Structure
Glucosides consist of a glucose molecule attached to another functional group or molecule. The bond between the glucose and the other molecule is known as a glycosidic bond. This bond can be either an alpha or beta linkage, depending on the orientation of the glucose molecule.
Types of Glucosides
There are several types of glucosides, classified based on the nature of the aglycone (the non-sugar part of the molecule):
- Cyanogenic glucosides: These release hydrogen cyanide when hydrolyzed. They are found in plants like cassava and bitter almonds.
- Saponins: These are glucosides with soap-like properties and are found in plants like soapwort and ginseng.
- Cardiac glycosides: These affect the heart and are found in plants like foxglove.
Biological Role
Glucosides play various roles in biological systems. They can serve as energy storage molecules, as in the case of starch and glycogen, or as protective agents, deterring herbivores and pathogens. Some glucosides are involved in signaling pathways within plants.
Applications
Glucosides have numerous applications in industry and medicine. They are used in the production of detergents, cosmetics, and pharmaceuticals. For example, decyl glucoside is a mild non-ionic surfactant used in personal care products.
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Contributors: Prab R. Tumpati, MD