Glucuronide
Glucuronide
Glucuronide (pronunciation: glu·cu·ro·nide) is a biochemical substance that plays a significant role in the metabolism of various substances in the body.
Etymology
The term 'Glucuronide' is derived from 'Glucuronic acid', a derivative of glucose, and the suffix '-ide' which is used in chemistry to denote a binary compound.
Definition
Glucuronides are substances produced in the body through a biochemical process known as glucuronidation. This process involves the addition of glucuronic acid to a substance, thereby increasing its water solubility and facilitating its excretion from the body. Glucuronides are thus important in the detoxification and elimination of potentially harmful substances, including drugs and endogenous compounds.
Related Terms
- Glucuronidation: The process by which glucuronic acid is added to a substance to form a glucuronide.
- Glucuronic acid: A derivative of glucose that is added to substances to form glucuronides.
- Metabolism: The set of life-sustaining chemical reactions in organisms.
- Detoxification: The physiological or medicinal removal of toxic substances from a living organism.
- Excretion: The process by which waste products are eliminated from the body.
See Also
- Phase II biotransformation: The process in which a small polar group is added to a substance to improve its excretion.
- Drug metabolism: The metabolic breakdown of drugs by living organisms.
External links
- Medical encyclopedia article on Glucuronide
- Wikipedia's article - Glucuronide
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