Grading (tumors)
Grading (tumors)
Grading (tumors) is a method used by medical professionals to classify tumors according to their biological behavior, specifically their cellular differentiation and rate of cell division. This is an important aspect of cancer diagnosis and treatment, as the grade of a tumor can influence its prognosis and the choice of treatment.
Definition
Tumor grading is a system used to classify a malignant tumor in terms of how abnormal the tumor cells and the tumor tissue look under a microscope. It is an attempt to approximate the aggressive behavior of the tumor. Higher grade tumors tend to grow and spread more quickly than lower grade tumors.
Grading Systems
There are several systems for grading tumors, and each one is specific to the type of cancer being graded. The most common systems are the Gleason Grading System, used for prostate cancer, and the Bloom-Richardson Grading System, used for breast cancer.
Gleason Grading System
The Gleason Grading System is used to grade prostate cancer. The system uses numbers from 1 to 5 to describe how much the cancerous tissue looks like normal prostate tissue. A lower number indicates a slower-growing cancer, while a higher number indicates a faster-growing cancer.
Bloom-Richardson Grading System
The Bloom-Richardson Grading System is used to grade breast cancer. This system uses numbers from 1 to 3 to describe how much the cancerous tissue looks like normal breast tissue. A lower number indicates a slower-growing cancer, while a higher number indicates a faster-growing cancer.
Importance of Tumor Grading
Tumor grading is an important part of cancer diagnosis and treatment. The grade of a tumor can influence its prognosis and the choice of treatment. For example, a high-grade tumor may require more aggressive treatment than a low-grade tumor.
See Also
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