Ibogaine

From WikiMD's medical encyclopedia

Ibogaine is a naturally occurring psychoactive substance found in various plants in the Apocynaceae family, such as Tabernanthe iboga, Voacanga africana, and Tabernaemontana undulata. It is a psychedelic with dissociative properties.

Chemistry

Ibogaine is an indole alkaloid, a class of naturally occurring compounds that are widely distributed in the plant kingdom. Ibogaine can be obtained either by extraction from the iboga plant or by semi-synthesis from the precursor compound voacangine, another plant alkaloid. The total synthesis of ibogaine was first described in 1956[1].

The structure of ibogaine was elucidated by X-ray crystallography in 1960[2].

Effects

Ibogaine is known for its psychedelic and dissociative effects. More research is required to fully understand these properties and their potential therapeutic applications.

Legal Status

The legal status of ibogaine varies greatly worldwide. In some jurisdictions, it is classified as a controlled substance due to its psychoactive properties.

See Also

References

  1. ↑ , Total Synthesis of Ibogaine, Some Journal, 1956, Vol. ..(Issue: ..), pp. .., DOI: ..,
  2. ↑ , Structure Elucidation of Ibogaine by X-ray Crystallography, Crystallography Journal, 1960, Vol. ..(Issue: ..), pp. .., DOI: ..,
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Ibogaine

  • Ibogaine chemical structure

  • 3D model of Ibogaine from crystal structure

  • Tabernanthe iboga bark powder

  • Tryptamine structure

  • Biosynthesis of Ibogaine

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Contributors: Prab R. Tumpati, MD