Iotrolan

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Iotrolan

A non-ionic, water-soluble contrast agent


Iotrolan
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Iotrolan is a non-ionic, water-soluble contrast agent used in medical imaging to enhance the visibility of internal structures in radiographic procedures. It is particularly utilized in computed tomography (CT) scans and angiography.

Properties

Iotrolan is known for its low osmolality and high viscosity, which contribute to its safety profile and effectiveness. Its non-ionic nature reduces the risk of adverse reactions compared to ionic contrast agents. The chemical structure of Iotrolan includes iodine atoms, which are responsible for its radiopacity.

Uses

Iotrolan is primarily used in:

Mechanism of Action

As a contrast agent, Iotrolan works by increasing the contrast of the images produced during radiographic procedures. The iodine atoms in Iotrolan absorb X-rays, making the blood vessels, organs, and other tissues more visible on the radiographic film or digital image.

Administration

Iotrolan is administered intravenously or intrathecally, depending on the type of imaging procedure. The dosage and method of administration are determined by the specific requirements of the imaging study and the patient's condition.

Side Effects

Common side effects of Iotrolan may include:

  • Nausea
  • Vomiting
  • Headache
  • Dizziness

Serious but rare side effects can include:

  • Allergic reactions
  • Kidney dysfunction
  • Cardiovascular issues

Precautions

Patients with a history of allergies to contrast agents, kidney disease, or cardiovascular disease should inform their healthcare provider before undergoing procedures involving Iotrolan. Adequate hydration before and after the procedure is recommended to help eliminate the contrast agent from the body.

See Also

References


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Contributors: Prab R. Tumpati, MD