Metreleptin
Metreleptin
Metreleptin (pronounced: meh-treh-lep-tin) is a synthetic form of the hormone leptin, used in the treatment of complications arising from leptin deficiency in certain individuals.
Etymology
The term "Metreleptin" is derived from the Greek words "metra", meaning "mother", and "leptos", meaning "thin". This is in reference to the hormone's role in regulating body weight and energy balance.
Usage
Metreleptin is used to treat the complications of leptin deficiency in individuals with congenital or acquired generalized lipodystrophy. It is also used in the treatment of rare metabolic diseases, including Berardinelli-Seip congenital lipodystrophy and Lawrence syndrome.
Mechanism of Action
Metreleptin works by replacing the leptin that is missing in patients with lipodystrophy. Leptin is a hormone that is produced in the fat cells of the body. It is responsible for regulating body weight by signaling the brain to reduce appetite and burn fat stored in the body.
Side Effects
Common side effects of Metreleptin include headache, weight loss, and abdominal pain. In rare cases, it can cause serious side effects such as development of antibodies that neutralize the medication's effect, and lymphoma.
Related Terms
External links
- Medical encyclopedia article on Metreleptin
- Wikipedia's article - Metreleptin
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