Eliglustat
Eliglustat (pronunciation: eh-lih-GLOO-stat) is a medication used in the treatment of Gaucher's disease. It is specifically used for type 1 Gaucher's disease in adults who are unable to receive enzyme replacement therapy.
Etymology
The name "Eliglustat" is derived from the chemical name of the drug, which is N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)propan-2-yl]octanamide.
Pharmacology
Eliglustat works by inhibiting the enzyme glucosylceramide synthase, which is involved in the production of glucocerebroside. This reduces the accumulation of glucocerebroside in the body, which is the cause of Gaucher's disease.
Usage
Eliglustat is taken orally, usually twice a day. It can be taken with or without food. The dosage is based on the patient's weight, medical condition, and response to treatment.
Side Effects
Common side effects of Eliglustat include fatigue, headache, nausea, and diarrhea. More serious side effects can include irregular heartbeat and a low number of blood cells.
Related Terms
See Also
External links
- Medical encyclopedia article on Eliglustat
- Wikipedia's article - Eliglustat
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