Mutanome
Mutanome
Mutanome (pronunciation: myoo-tuh-nohm) is a term used in the field of oncology and genomics to describe the complete set of mutations in the genome of a tumor.
Etymology
The term 'Mutanome' is a portmanteau of the words 'mutation' and 'genome'. It was coined to describe the unique set of mutations that each tumor possesses, which can be used for personalized cancer therapy.
Definition
The mutanome is the complete set of mutations found in the genome of a tumor. These mutations can include single nucleotide polymorphisms (SNPs), insertions and deletions (indels), and copy number variations (CNVs). The mutanome is unique to each tumor and can provide valuable information for personalized cancer therapy.
Related Terms
- Genome: The complete set of genes or genetic material present in a cell or organism.
- Mutation: A change in the DNA sequence that makes up a gene.
- Oncology: The study of cancer and tumors.
- Genomics: The study of genomes, including the sequencing, mapping, and analysis of an organism's genetic material.
- Single nucleotide polymorphisms (SNPs): A type of genetic variation that occurs when a single nucleotide in the genome sequence is altered.
- Insertions and deletions (indels): Types of mutations in which nucleotides are added or removed from a DNA sequence.
- Copy number variations (CNVs): A type of structural variation where sections of the genome are repeated and the number of repeats in the genome varies between individuals in the human population.
External links
- Medical encyclopedia article on Mutanome
- Wikipedia's article - Mutanome
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