Oncofertility

From WikiMD's medical encyclopedia

Oncofertility is a subfield of medicine that bridges oncology, the medical field dealing with cancer, and reproductive medicine. It focuses on the reproductive health and fertility preservation in patients undergoing cancer treatment. The term "oncofertility" was coined to address the complex reproductive needs and concerns of cancer patients and survivors.

Overview

Cancer treatments, such as chemotherapy, radiation therapy, and surgery, can adversely affect fertility in both men and women. Oncofertility aims to provide fertility preservation options and support to individuals of reproductive age who are diagnosed with cancer. This interdisciplinary field combines efforts from oncologists, reproductive specialists, researchers, and counselors to offer comprehensive care.

Fertility Preservation Methods

Several fertility preservation methods are available for cancer patients. The choice of method depends on the patient's age, type of cancer, treatment plan, and personal preferences.

For Women

  • Cryopreservation of Oocytes or Embryos: This involves the freezing of eggs or embryos for future use. It is the most commonly recommended option for women.
  • Ovarian Tissue Freezing: This experimental technique involves the removal and freezing of ovarian tissue before cancer treatment, to be reimplanted at a later stage.
  • Ovarian Suppression: The use of hormonal therapy to protect the ovaries during chemotherapy.

For Men

  • Sperm Cryopreservation: The collection and freezing of sperm before cancer treatment.
  • Testicular Tissue Freezing: An experimental approach involving the freezing of testicular tissue for prepubescent boys.

Ethical and Psychological Considerations

Oncofertility raises several ethical and psychological issues, including the cost of fertility preservation, access to services, and the emotional impact of making fertility-related decisions while facing a cancer diagnosis. Counseling and support services play a crucial role in helping patients navigate these challenges.

Research and Future Directions

Research in oncofertility is focused on improving existing fertility preservation techniques and developing new methods. Advances in cryobiology, the study of freezing biological material, and regenerative medicine hold promise for future fertility preservation options.

Conclusion

Oncofertility is a vital field that addresses the reproductive concerns of cancer patients, offering hope for biological parenthood post-cancer treatment. It exemplifies the importance of a multidisciplinary approach in providing holistic care to cancer patients.


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Contributors: Prab R. Tumpati, MD