Pegademase bovine
Pegademase Bovine
Pegademase bovine (pronunciation: peh-gah-deh-mase boh-vine) is a medicinal drug used in the treatment of adenosine deaminase deficiency (ADA deficiency), a rare genetic disorder that damages the immune system and causes severe combined immunodeficiency (SCID).
Etymology
The term "Pegademase bovine" is derived from the words "pegylated", "adenosine deaminase", and "bovine". "Pegylated" refers to the process of attaching polyethylene glycol (PEG) to the molecule, "adenosine deaminase" is an enzyme that is deficient in ADA deficiency, and "bovine" indicates that the enzyme is derived from cows.
Usage
Pegademase bovine is used to replace the missing or deficient adenosine deaminase enzyme in patients with ADA deficiency. This helps to restore the function of the immune system and reduce the risk of severe infections.
Related Terms
- Adenosine Deaminase Deficiency: A rare genetic disorder that damages the immune system and causes severe combined immunodeficiency (SCID).
- Immunodeficiency: A state in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent.
- Enzyme: A substance produced by a living organism which acts as a catalyst to bring about a specific biochemical reaction.
- Genetic Disorder: A genetic problem caused by one or more abnormalities in the genome, especially a condition that is present from birth (congenital).
See Also
- Polyethylene Glycol: A polyether compound with many applications from industrial manufacturing to medicine.
- Severe Combined Immunodeficiency: A genetic disorder characterized by the disturbed development of functional T cells and B cells caused by numerous genetic mutations that result in differing clinical presentations.
External links
- Medical encyclopedia article on Pegademase bovine
- Wikipedia's article - Pegademase bovine
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