Pramiracetam

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Pramiracetam.svg

Pramiracetam is a nootropic drug derived from piracetam, and is part of the racetam family of cognitive enhancers. It is known for its potential to improve memory, learning, and overall cognitive function.

Chemical Structure and Properties

Pramiracetam is a derivative of piracetam, with the chemical name 2-(2-oxopyrrolidin-1-yl)-N-(2-(diisopropylamino)ethyl)acetamide. It has a molecular formula of C14H27N3O2 and a molecular weight of 269.38 g/mol. The drug is characterized by its high potency and long duration of action compared to other racetams.

Mechanism of Action

The exact mechanism of action of pramiracetam is not fully understood. However, it is believed to enhance cholinergic neurotransmission by increasing the uptake of choline in the hippocampus, a region of the brain associated with memory formation. This action is thought to facilitate the synthesis of acetylcholine, a neurotransmitter crucial for cognitive processes.

Uses and Benefits

Pramiracetam is primarily used for its potential cognitive-enhancing effects. It is often utilized to improve:

Some studies suggest that pramiracetam may be beneficial in the treatment of cognitive decline associated with neurodegenerative diseases such as Alzheimer's disease and dementia.

Dosage and Administration

Pramiracetam is typically administered orally, with recommended dosages ranging from 400 mg to 1200 mg per day, divided into two or three doses. It is advised to take pramiracetam with food to enhance absorption.

Side Effects

Pramiracetam is generally well-tolerated, but some users may experience side effects, including:

These side effects are usually mild and can often be mitigated by adjusting the dosage or taking the drug with food.

Legal Status

The legal status of pramiracetam varies by country. In some regions, it is available as a dietary supplement, while in others, it may be classified as a prescription drug or be entirely unregulated.

See Also

References



External Links


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Contributors: Prab R. Tumpati, MD