Primary hyperaldosteronism

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Primary Hyperaldosteronism

Primary hyperaldosteronism, also known as Conn's syndrome, is a disorder characterized by the overproduction of aldosterone hormone from the adrenal glands. This overproduction leads to a decrease in potassium levels and an increase in sodium and water retention, causing high blood pressure (hypertension).

Pronunciation

Primary Hyperaldosteronism: /ˈpraɪməriː/, /ˌhaɪpərˌældəˈrɒstərəˌnɪzəm/

Etymology

The term "Primary Hyperaldosteronism" is derived from the following roots:

  • Primary: from Latin 'primarius' meaning 'of the first rank'
  • Hyper: from Greek 'hyper' meaning 'over, above, or excessive'
  • Aldosterone: from Latin 'alde' meaning 'of the adrenal gland' and 'sterone' meaning 'steroid hormone'
  • -ism: from Greek '-ismos' indicating a condition or disease

Related Terms

  • Secondary hyperaldosteronism: A condition where the excess aldosterone is caused by something outside the adrenal glands.
  • Hypokalemia: A condition characterized by low potassium levels in the blood, a common symptom of primary hyperaldosteronism.
  • Hypertension: High blood pressure, a common symptom of primary hyperaldosteronism.

Symptoms

Primary hyperaldosteronism can cause a variety of symptoms, including:

  • High blood pressure
  • Muscle weakness and cramps
  • Excessive thirst and urination
  • Headaches
  • Fatigue

Diagnosis

Diagnosis of primary hyperaldosteronism typically involves blood tests to measure levels of potassium, aldosterone, and renin, a hormone that regulates blood pressure. Imaging tests such as CT scans or MRIs may also be used to identify any abnormalities in the adrenal glands.

Treatment

Treatment for primary hyperaldosteronism depends on the underlying cause. If a tumor in the adrenal gland is causing the condition, surgery may be required. In other cases, medication to block the effects of aldosterone or to lower blood pressure may be prescribed.

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