RS-102221
Selective 5-HT2C receptor antagonist
RS-102221 is a chemical compound that acts as a selective antagonist for the 5-HT2C receptor, a subtype of the serotonin receptor. It is used in scientific research to study the role of the 5-HT2C receptor in various physiological and pathological processes.
Pharmacology
RS-102221 has been shown to have high affinity and selectivity for the 5-HT2C receptor over other serotonin receptor subtypes, such as the 5-HT2A receptor and 5-HT2B receptor. This selectivity makes it a valuable tool for researchers investigating the specific functions of the 5-HT2C receptor.
Research Applications
RS-102221 is used in a variety of research contexts, including studies on anxiety, depression, and schizophrenia. By blocking the 5-HT2C receptor, researchers can observe changes in behavior and physiology that may be linked to these conditions. Additionally, RS-102221 is used to explore the role of the 5-HT2C receptor in appetite regulation and weight control.
Mechanism of Action
As a 5-HT2C receptor antagonist, RS-102221 binds to the receptor and prevents the action of serotonin (5-HT) at this site. This inhibition can alter the downstream signaling pathways that are normally activated by serotonin binding, leading to various physiological effects.
Chemical Properties
RS-102221 has the chemical formula C19H18Cl2N3O and a molecular weight of 390.27 g/mol. It is characterized by the presence of a dichlorophenyl group and a tetrahydroisoquinoline structure.
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