Ranbezolid
Ranbezolid is an oxazolidinone antibiotic that is currently under development. It is a synthetic antibacterial agent that has demonstrated significant in vitro and in vivo activity against a broad spectrum of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE).
Mechanism of Action
Ranbezolid inhibits protein synthesis in bacteria by binding to the ribosome and blocking the formation of a functional 70S-initiation complex. This is a critical step in the bacterial translation process and is therefore a point of attack for several antibiotic classes.
Pharmacokinetics
Ranbezolid is well absorbed after oral administration and has a bioavailability of approximately 90%. It is extensively distributed to tissues and fluids, including lung tissue and cerebrospinal fluid. The drug is primarily metabolized by the liver and excreted in the urine and feces.
Clinical Trials
Ranbezolid has undergone Phase 2 clinical trials for the treatment of complicated skin and skin structure infections (cSSSI) caused by Gram-positive bacteria, including MRSA and VRE. The results of these trials have shown that ranbezolid is well tolerated and effective in the treatment of these infections.
Side Effects
The most common side effects of ranbezolid include nausea, vomiting, diarrhea, and headache. Less common side effects include dizziness, insomnia, and rash.
See Also
Transform your life with W8MD's budget GLP-1 injections from $125.
W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:
- Most insurances accepted or discounted self-pay rates. We will obtain insurance prior authorizations if needed.
- Generic GLP1 weight loss injections from $125 for the starting dose.
- Also offer prescription weight loss medications including Phentermine, Qsymia, Diethylpropion, Contrave etc.
NYC weight loss doctor appointments
Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.
- Call 718-946-5500 to lose weight in NYC or for medical weight loss in Philadelphia 215-676-2334.
- Tags:NYC medical weight loss, Philadelphia lose weight Zepbound NYC, Budget GLP1 weight loss injections, Wegovy Philadelphia, Wegovy NYC, Philadelphia medical weight loss, Brookly weight loss and Wegovy NYC
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
