Ranpirnase

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Ranpirnase

Ranpirnase (pronounced ran-PIR-nase) is a ribonuclease enzyme that is derived from the Northern Leopard Frog (Rana pipiens). It is primarily used in the field of oncology as a potential treatment for various types of cancer.

Etymology

The term "Ranpirnase" is a combination of the genus name of the Northern Leopard Frog, Rana, and "pirnase", a suffix used to denote a type of ribonuclease enzyme.

Function

Ranpirnase works by breaking down RNA molecules in cancer cells, thereby inhibiting their growth and proliferation. It is a type of antineoplastic agent, which are drugs that prevent the development, growth, or proliferation of malignant cells.

Clinical Use

Ranpirnase has been studied in clinical trials for the treatment of malignant mesothelioma, a rare type of cancer that affects the thin layer of tissue that covers most of your internal organs. It has also been investigated for its potential use in treating Kaposi's sarcoma, a type of cancer that causes patches of abnormal tissue to grow under the skin, in the lining of the mouth, nose, and throat, or in other organs.

Related Terms

  • Ribonuclease: An enzyme that catalyzes the degradation of RNA into smaller components.
  • Antineoplastic agent: A substance that inhibits the growth and spread of cancerous cells.
  • Malignant mesothelioma: A rare type of cancer that develops in the thin layer of tissue that covers most of your internal organs.
  • Kaposi's sarcoma: A type of cancer that causes patches of abnormal tissue to grow under the skin, in the lining of the mouth, nose, and throat, or in other organs.

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