Staurosporine
Staurosporine
Staurosporine (pronunciation: stow-ros-por-een) is a potent inhibitor of protein kinases, which are enzymes that modify other proteins by chemically adding phosphate groups to them.
Etymology
The term "Staurosporine" is derived from the bacterium Streptomyces staurosporeus, from which it was first isolated in 1977. The suffix "-ine" is commonly used in chemistry to denote a particular group or class of compounds.
Function
Staurosporine is known for its ability to inhibit a wide range of protein kinases, which play crucial roles in many cellular processes, including cell division, signal transduction, and apoptosis (programmed cell death). By inhibiting these enzymes, staurosporine can affect these processes and has therefore been studied for its potential use in cancer therapy.
Related Terms
- Protein Kinase: An enzyme that modifies other proteins by chemically adding phosphate groups to them.
- Inhibitor: A substance that slows down or prevents a particular chemical reaction or other process, or that reduces the activity of a particular reactant, catalyst, or enzyme.
- Apoptosis: The death of cells which occurs as a normal and controlled part of an organism's growth or development.
- Signal Transduction: The process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.
- Cell Division: The process by which a parent cell divides into two or more daughter cells.
External links
- Medical encyclopedia article on Staurosporine
- Wikipedia's article - Staurosporine
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski