Stroma of cornea
Stroma of cornea is the thickest layer of the cornea, making up about 90% of the cornea's thickness. It is located between the Bowman's layer and the Descemet's membrane. The stroma is composed primarily of water and collagen fibers, which give the cornea its strength and elasticity.
Structure
The stroma of the cornea is composed of approximately 200 thin layers of collagen fibers. These fibers are arranged in a regular, parallel pattern that is essential for the cornea's transparency. The collagen fibers are produced by cells called keratocytes, which are found between the layers of collagen.
In addition to collagen, the stroma also contains a small amount of proteoglycans, which are proteins that are heavily glycosylated. The proteoglycans fill the spaces between the collagen fibers and help to maintain the regular arrangement of the fibers.
Function
The primary function of the stroma is to provide strength and elasticity to the cornea. The regular arrangement of the collagen fibers allows light to pass through the cornea without scattering, which is essential for clear vision.
The stroma also plays a role in the cornea's ability to heal after injury. The keratocytes in the stroma can transform into a type of cell called a fibroblast, which can produce new collagen fibers to repair damage to the cornea.
Clinical significance
Abnormalities in the stroma can lead to a variety of corneal diseases. For example, in keratoconus, the collagen fibers in the stroma become irregularly arranged, leading to a thinning and bulging of the cornea. In corneal dystrophy, deposits of material can accumulate in the stroma, interfering with its transparency.
Treatment for stromal disorders can include corneal transplantation, in which the diseased cornea is replaced with a healthy donor cornea, or corneal cross-linking, a procedure that strengthens the collagen fibers in the stroma to prevent further thinning and bulging.
See also
Stroma of cornea
Transform your life with W8MD's budget GLP-1 injections from $125.
W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:
- Most insurances accepted or discounted self-pay rates. We will obtain insurance prior authorizations if needed.
- Generic GLP1 weight loss injections from $125 for the starting dose.
- Also offer prescription weight loss medications including Phentermine, Qsymia, Diethylpropion, Contrave etc.
NYC weight loss doctor appointments
Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.
- Call 718-946-5500 to lose weight in NYC or for medical weight loss in Philadelphia 215-676-2334.
- Tags:NYC medical weight loss, Philadelphia lose weight Zepbound NYC, Budget GLP1 weight loss injections, Wegovy Philadelphia, Wegovy NYC, Philadelphia medical weight loss, Brookly weight loss and Wegovy NYC
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
