TNFRSF18
TNFRSF18 (pronounced as T-N-F-R-S-F-eighteen), also known as Tumor Necrosis Factor Receptor Superfamily Member 18, is a protein that in humans is encoded by the TNFRSF18 gene.
Pronunciation
The term TNFRSF18 is pronounced as "T-N-F-R-S-F-eighteen".
Etymology
The term TNFRSF18 is an abbreviation for "Tumor Necrosis Factor Receptor Superfamily Member 18". The name is derived from its function and classification. "Tumor Necrosis Factor" refers to a group of cytokines that can cause cell death (apoptosis), "Receptor Superfamily" refers to a large and diverse group of proteins that are involved in signal transduction, and "Member 18" indicates that it is the 18th member of this family.
Function
TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.
Related Terms
- Tumor Necrosis Factor (TNF): A cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.
- Receptor Superfamily: A large and diverse group of proteins that are involved in signal transduction.
- Apoptosis: A form of programmed cell death that occurs in multicellular organisms.
- Signal Transduction: The process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.
- Cytokine: A type of protein that is important in cell signaling.
External links
- Medical encyclopedia article on TNFRSF18
- Wikipedia's article - TNFRSF18
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