Adinazolam
Adinazolam (pronounced: ad-in-az-oh-lam) is a benzodiazepine derivative, and more specifically, a triazolobenzodiazepine (TBZD), which are benzodiazepines fused with a triazole ring. It possesses anxiolytic, anticonvulsant, sedative, and antidepressant properties.
Etymology
The name "Adinazolam" is derived from the chemical structure of the drug. The prefix "Adi-" is derived from its chemical structure, specifically the addition of a triazole ring to the diazepam molecule. The "-nazolam" suffix is common among other benzodiazepines, such as alprazolam, estazolam, and midazolam.
Pharmacology
Adinazolam was developed by Dr. Jackson B. Hester, who was seeking to enhance the antidepressant properties of alprazolam, which he also developed. Adinazolam is metabolized into several metabolites, the main one being N-desmethyladinazolam, which is responsible for most of the drug's activity.
Medical Uses
Adinazolam is used for the treatment of anxiety disorders and panic disorder. It may also be used as an adjunct treatment for major depressive disorder when first-line treatments have failed or are not tolerated.
Side Effects
Like other benzodiazepines, adinazolam has the potential for abuse and may cause physical dependence and withdrawal symptoms if used over a long period of time. Other side effects may include drowsiness, dizziness, and impaired coordination.
See Also
External links
- Medical encyclopedia article on Adinazolam
- Wikipedia's article - Adinazolam
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