D'Espine sign

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D'Espine Sign

D'Espine sign (/dɛˈspin/; named after Edmond D'Espine, a Swiss physician) is a clinical sign in medicine that indicates the presence of a mediastinal mass, often associated with tuberculosis or lymphoma.

Pronunciation

The term is pronounced as /dɛˈspin/.

Etymology

The sign is named after Edmond D'Espine, a Swiss physician who first described it in the late 19th century.

Definition

D'Espine sign is a clinical sign characterized by the presence of a continuous, dull, and high-pitched sound heard on auscultation along the upper part of the vertebral column. This sign is often associated with mediastinal masses, particularly those caused by tuberculosis or lymphoma.

Clinical Significance

The presence of D'Espine sign is indicative of a mediastinal mass, which could be due to various conditions such as tuberculosis, lymphoma, or other neoplasms. It is particularly useful in the diagnosis of Pott's disease, a form of tuberculosis that affects the spine.

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