Giant-cell fibroblastoma

Giant-cell fibroblastoma

Giant-cell fibroblastoma (pronunciation: jai-ant-sel fai-bro-blas-to-ma) is a rare type of soft tissue sarcoma that primarily affects children and young adults.

Etymology

The term "Giant-cell fibroblastoma" is derived from the characteristics of the tumor. "Giant-cell" refers to the large, multinucleated cells that are often seen in these tumors. "Fibroblastoma" is derived from "fibroblast", a type of cell that produces collagen and other fibers, and "-oma", a suffix used in medical terminology to indicate a tumor or neoplasm.

Definition

Giant-cell fibroblastoma is a rare, benign tumor that typically occurs in the dermis or subcutaneous tissue. It is characterized by the presence of large, multinucleated giant cells and fibroblasts. The tumor is most commonly found in children and young adults, with a higher prevalence in males.

Symptoms

Symptoms of giant-cell fibroblastoma may include a painless, slow-growing mass or lump, usually located on the trunk, arms, or legs. The tumor may also cause functional impairment depending on its location.

Diagnosis

Diagnosis of giant-cell fibroblastoma is typically made through a combination of physical examination, imaging studies such as MRI or CT scan, and histopathological examination of a biopsy specimen.

Treatment

Treatment for giant-cell fibroblastoma typically involves surgical removal of the tumor. In some cases, radiation therapy or chemotherapy may be used, particularly if the tumor is large or has spread to other parts of the body.

Prognosis

The prognosis for individuals with giant-cell fibroblastoma is generally good, particularly if the tumor is detected early and can be completely removed. However, the tumor can recur, so regular follow-up is important.

Related Terms

• Soft tissue sarcoma
• Tumor
• Fibroblast
• MRI
• CT scan
• Radiation therapy
• Chemotherapy

External links

• Medical encyclopedia article on Giant-cell fibroblastoma
• Wikipedia's article - Giant-cell fibroblastoma

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