Human disease network
Human Disease Network
The Human Disease Network (HDN) (pronounced: /ˈhjuːmən diːˈziːz ˈnɛtwɜːrk/) is a comprehensive biological database that maps and catalogues the relationships between various diseases and disorders in the human body. The HDN is a crucial tool in medical research, aiding in the understanding of disease mechanisms, genetic predispositions, and potential therapeutic strategies.
Etymology
The term "Human Disease Network" is derived from the English words "human" (referring to Homo sapiens), "disease" (from the Old French desaise, meaning lack of ease), and "network" (from the English net and work, indicating a complex interconnected system).
Structure
The Human Disease Network is structured as a graph, where each node represents a disease and each edge represents a genetic or pathological connection between two diseases. The HDN includes a wide range of diseases, from common conditions like diabetes and heart disease, to rare genetic disorders.
Applications
The HDN is used in various fields of medical research, including epidemiology, genomics, and pharmacology. By understanding the connections between diseases, researchers can identify potential genetic risk factors, develop new therapeutic strategies, and predict disease progression.
Related Terms
- Biological database
- Disease
- Disorder
- Medical research
- Genetic
- Therapeutic
- Graph theory
- Diabetes
- Heart disease
- Epidemiology
- Genomics
- Pharmacology
External links
- Medical encyclopedia article on Human disease network
- Wikipedia's article - Human disease network
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