Intercalated cell

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Intercalated cell

Intercalated cells (pronunciation: in-ter-kal-ay-ted cells) are specialized cells found in the kidneys, specifically in the collecting duct system. They play a crucial role in maintaining the body's acid-base balance and electrolyte balance.

Etymology

The term "intercalated" is derived from the Latin word "intercalare", which means "to insert a day". In this context, it refers to the cells being 'inserted' or interspersed among the principal cells in the collecting duct system.

Function

Intercalated cells are responsible for the reabsorption of bicarbonate ions and the secretion of hydrogen ions. This helps in maintaining the pH of the body's fluids. There are two types of intercalated cells - Type A and Type B. Type A cells are involved in acid secretion, while Type B cells are involved in bicarbonate secretion.

Related Terms

  • Principal cell: These cells are found alongside intercalated cells in the collecting duct system. They are involved in the reabsorption of sodium ions and water, and the secretion of potassium ions.
  • Collecting duct: This is a part of the kidney's nephron where the final concentration of urine occurs. It contains both principal cells and intercalated cells.
  • Acid-base balance: This refers to the balance between the production and elimination of hydrogen ions in the body. Intercalated cells play a key role in maintaining this balance.
  • Electrolyte balance: This refers to the balance of ions in the body's fluids. Intercalated cells contribute to this balance by reabsorbing bicarbonate ions and secreting hydrogen ions.

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