Sulfadoxine/pyrimethamine
Sulfadoxine/Pyrimethamine
Sulfadoxine/Pyrimethamine (pronunciation: sul-fa-DOX-een/peer-i-METH-a-meen) is a combination medication used primarily to treat malaria. It is also used to prevent malaria in areas where malaria is known to be sensitive to its effects.
Etymology
The name "Sulfadoxine/Pyrimethamine" is derived from the two active ingredients in the medication: Sulfadoxine, a long-lasting sulfonamide, and Pyrimethamine, a dihydrofolate reductase inhibitor.
Usage
Sulfadoxine/Pyrimethamine is typically used in combination with other antimalarial drugs to treat and prevent malaria. It is not typically used alone due to the risk of drug resistance.
Side Effects
Common side effects of Sulfadoxine/Pyrimethamine include nausea, vomiting, and diarrhea. More serious side effects may include bone marrow suppression, liver problems, and severe skin rashes.
Related Terms
- Malaria: A disease caused by a plasmodium parasite, transmitted by the bite of infected mosquitoes.
- Sulfonamide: A group of drugs used to treat bacterial infections.
- Pyrimethamine: A medication used with leucovorin to treat toxoplasmosis and cystoisosporiasis.
- Dihydrofolate reductase inhibitor: A type of drug that blocks the action of dihydrofolate reductase, an enzyme that cells need to live.
External links
- Medical encyclopedia article on Sulfadoxine/pyrimethamine
- Wikipedia's article - Sulfadoxine/pyrimethamine
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