Typical antipsychotic

Typical antipsychotics (pronunciation: /ˈtɪpɪkəl ˌæntɪsaɪˈkɒtɪks/) are a class of antipsychotic drugs primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. They are also known as first-generation antipsychotics (FGAs).

Etymology

The term "typical antipsychotic" is derived from their earlier discovery and use in the mid-20th century, distinguishing them from the newer, second-generation or "atypical" antipsychotics.

Pharmacology

Typical antipsychotics are classified according to their chemical structure. They include phenothiazines, butyrophenones, and thioxanthenes. They primarily work by blocking dopamine receptors, specifically the D2 receptors, in the brain.

Related Terms

Phenothiazines: A group of typical antipsychotics that includes drugs like chlorpromazine and fluphenazine.
Butyrophenones: This group includes haloperidol, a commonly used typical antipsychotic.
Thioxanthenes: This group includes drugs like thiothixene.
Dopamine: A neurotransmitter in the brain that is primarily blocked by typical antipsychotics.
Schizophrenia: A mental disorder often treated with typical antipsychotics.
Bipolar disorder: Another mental disorder where typical antipsychotics may be used.

External links

Medical encyclopedia article on Typical antipsychotic
Wikipedia's article - Typical antipsychotic

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Typical antipsychotic