11-Hydroxy-THC

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11-Hydroxy-THC

11-Hydroxy-Δ9-tetrahydrocannabinol (commonly known as 11-Hydroxy-THC) is a psychoactive metabolite of THC, the active component in cannabis.

Pronunciation

  • 11-Hydroxy-THC: /ˌɛlɪvən haɪˈdrɒksi tiːeɪtʃˈsiː/

Etymology

The term "11-Hydroxy-THC" is derived from its chemical structure. The "11-Hydroxy" part refers to the hydroxy group attached at the 11th carbon atom in the THC molecule.

Description

When THC is ingested orally, it undergoes a process known as first-pass metabolism in the liver, where it is converted into 11-Hydroxy-THC. This metabolite is more potent than THC and has a longer half-life, leading to prolonged psychoactive effects.

Related Terms

  • THC: The primary psychoactive component in cannabis.
  • Cannabis: A genus of flowering plants in the family Cannabaceae, which is used for its psychoactive and medicinal properties.
  • Metabolite: A substance formed in or necessary for metabolism.
  • Psychoactive drug: A chemical substance that changes brain function and results in alterations in perception, mood, consciousness, cognition, or behavior.
  • First-pass metabolism: The metabolism of a drug or compound that occurs immediately after it enters the body and before it enters the general bloodstream.

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