5-TFMO-DMT

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5-TFMO-DMT

Chemical structure of 5-TFMO-DMT

5-TFMO-DMT is a synthetic compound belonging to the class of tryptamines, which are known for their psychoactive properties. This compound is a derivative of DMT (N,N-Dimethyltryptamine), a naturally occurring psychedelic substance found in various plants and animals.

Chemical Structure

5-TFMO-DMT is characterized by the presence of a trifluoromethoxy group at the 5-position of the indole ring. This modification distinguishes it from other tryptamines and potentially alters its pharmacological properties. The chemical structure of 5-TFMO-DMT can be represented as follows:

Chemical structure of 5-TFMO-DMT

Pharmacology

As a tryptamine derivative, 5-TFMO-DMT is believed to interact with the serotonin receptors in the brain, particularly the 5-HT2A receptor, which is commonly associated with the effects of psychedelic substances. The trifluoromethoxy group may influence the binding affinity and selectivity of the compound for these receptors.

Effects

The psychoactive effects of 5-TFMO-DMT are not well-documented, as it is a relatively novel compound. However, based on its structural similarity to other tryptamines, it may produce effects such as altered perception, mood changes, and visual hallucinations. The duration and intensity of these effects can vary depending on the dose and individual metabolism.

Synthesis

The synthesis of 5-TFMO-DMT involves the introduction of a trifluoromethoxy group to the indole ring of DMT. This process requires specialized knowledge in organic chemistry and access to specific reagents and equipment. The synthesis of such compounds is typically conducted in a laboratory setting under controlled conditions.

Legal Status

The legal status of 5-TFMO-DMT varies by country. In many jurisdictions, it may be classified as a controlled substance due to its structural similarity to other psychoactive tryptamines. Researchers and chemists must be aware of the legal implications of working with this compound.

Related Compounds

See Also

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Contributors: Prab R. Tumpati, MD