Adult-onset Still's disease

Adult-onset Still's disease (Pronunciation: /əˈdʌlt ˈɒnˌsɛt stɪlz diːˈziːz/) is a rare type of inflammatory arthritis that features fevers, rash and joint pain. Some people may have a single episode of Adult-onset Still's disease. In other people, the condition persists or recurs. This inflammation can destroy affected joints, particularly the wrists. Treatment involves medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids, that help control inflammation.

Etymology

The disease is named after Sir George Frederic Still (1868–1941), an English pediatrician. The term "adult-onset" differentiates it from a similar condition in children known as Juvenile idiopathic arthritis.

Symptoms

Symptoms of Adult-onset Still's disease include:

• Fever
• Rash
• Joint pain
• Sore throat
• Weight loss
• Abdominal pain
• Pneumonitis

Diagnosis

Diagnosis of Adult-onset Still's disease can be challenging as there is no specific diagnostic test. It is often a diagnosis of exclusion, meaning other conditions must be ruled out first. Blood tests, imaging and a physical exam can help confirm the diagnosis.

Treatment

Treatment for Adult-onset Still's disease primarily involves managing symptoms and preventing joint damage. Medications used include:

• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Corticosteroids
• Immunosuppressants

Prognosis

The prognosis for Adult-onset Still's disease varies. Some people experience a single episode and recover, while others may have recurring episodes or chronic symptoms.

See also

• Juvenile idiopathic arthritis
• Inflammatory arthritis
• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Corticosteroids

External links

• Medical encyclopedia article on Adult-onset Still's disease
• Wikipedia's article - Adult-onset Still's disease

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