Azasetron
Azasetron is a pharmaceutical drug used primarily as an antiemetic to prevent nausea and vomiting caused by chemotherapy and radiotherapy. It belongs to the class of drugs known as 5-HT3 receptor antagonists, which work by blocking the action of serotonin at the 5-HT3 receptors.
Mechanism of Action[edit]
Azasetron works by inhibiting the action of serotonin at the 5-HT3 receptors located in the central nervous system and the gastrointestinal tract. By blocking these receptors, azasetron prevents the activation of the vomiting center in the brain, thereby reducing the sensation of nausea and the occurrence of vomiting.
Uses[edit]
Azasetron is primarily used in the management of chemotherapy-induced nausea and vomiting (CINV) and radiotherapy-induced nausea and vomiting (RINV). It is often administered prior to the initiation of chemotherapy or radiotherapy to prevent these side effects.
Administration[edit]
Azasetron can be administered orally or intravenously. The dosage and route of administration depend on the severity of the symptoms and the specific needs of the patient.
Side Effects[edit]
Common side effects of azasetron include:
Serious side effects are rare but may include:
Contraindications[edit]
Azasetron is contraindicated in patients with a known hypersensitivity to the drug or any of its components. Caution is advised in patients with a history of cardiovascular disease.
Related Drugs[edit]
Other drugs in the same class of 5-HT3 receptor antagonists include:
See Also[edit]
References[edit]
External Links[edit]
-
 | This medical article is a stub. You can help WikiMD by expanding the page. |
