Intepirdine
Intepirdine
Intepirdine (pronounced in-tep-ir-dine) is a drug that was under development for the treatment of Alzheimer's disease and other neurodegenerative diseases.
Etymology
The name "Intepirdine" is derived from the Latin "inter", meaning "between", and "perdere", meaning "to lose". This refers to the drug's intended function of slowing the progression of cognitive decline in neurodegenerative diseases.
Pharmacology
Intepirdine is a 5-HT6 receptor antagonist. The 5-HT6 receptor is a subtype of the 5-HT receptor that binds the endogenous neurotransmitter serotonin. It is thought to play a significant role in the pathology of Alzheimer's disease.
Clinical Trials
Intepirdine was tested in a Phase III clinical trial for Alzheimer's disease, but the trial did not meet its primary efficacy endpoints. The drug was also tested in a Phase IIb trial for Huntington's disease, but the results were not statistically significant.
Related Terms
External links
- Medical encyclopedia article on Intepirdine
- Wikipedia's article - Intepirdine
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