Morphogenesis
Morphogenesis is the biological process that causes an organism to develop its shape. It is one of three fundamental aspects of developmental biology along with the control of cell growth and cellular differentiation, unified in the field of developmental biology.
Overview
Morphogenesis is a process that involves a complex series of events. It begins with the early stages of embryonic development and continues into adulthood. The process is controlled by a variety of genetic and environmental factors.
Mechanisms
Morphogenesis is driven by a number of mechanisms. These include cell growth, cell migration, cell adhesion, cell differentiation, and programmed cell death. Each of these mechanisms plays a crucial role in shaping the organism.
Role in Development
Morphogenesis plays a critical role in the development of an organism. It is responsible for the formation of the body plan and the differentiation of the cells into various tissues and organs. It also plays a role in the maintenance and repair of tissues and organs throughout the life of the organism.
Role in Disease
Abnormalities in morphogenesis can lead to a variety of diseases. These include birth defects, cancer, and degenerative diseases. Understanding the mechanisms of morphogenesis can therefore provide insights into the causes and potential treatments for these diseases.
See Also
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Contributors: Prab R. Tumpati, MD