Pathologic fracture

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Pathologic fracture
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Bone pain, swelling, deformity, loss of function
Complications	Nonunion, malunion, infection
Onset	Sudden, often with minimal or no trauma
Duration	Varies, depending on underlying cause and treatment
Types	N/A
Causes	Osteoporosis, bone metastasis, osteomyelitis, Paget's disease of bone, osteogenesis imperfecta
Risks	Cancer, chronic steroid use, bone diseases
Diagnosis	X-ray, CT scan, MRI, bone scan
Differential diagnosis	Traumatic fracture, bone cyst, benign bone tumor
Prevention	N/A
Treatment	Surgery, radiation therapy, chemotherapy, bisphosphonates
Medication	N/A
Prognosis	Depends on underlying condition and treatment
Frequency	Common in patients with cancer or osteoporosis
Deaths	N/A

Osteoporosis illustration

A pathologic fracture is a type of bone fracture that occurs in a bone affected by a disease, making it weaker than normal bone. This can be due to a variety of conditions, including osteoporosis, cancer, infection, or certain inherited bone disorders.

Causes

Pathologic fractures can be caused by a variety of conditions. The most common cause is metastatic bone disease, where cancer cells spread from their original site to the bones. Other causes include osteoporosis, a condition that weakens bones and makes them more likely to break, and Paget's disease of bone, a chronic disorder that can result in enlarged and misshapen bones. Infections, such as osteomyelitis, can also cause pathologic fractures.

Symptoms

The symptoms of a pathologic fracture can vary depending on the location and severity of the fracture. Common symptoms include pain at the site of the fracture, swelling, and difficulty moving the affected area. In some cases, a pathologic fracture may be the first sign of an underlying bone disease.

Diagnosis

Diagnosis of a pathologic fracture typically involves a combination of physical examination, medical history, and imaging tests. X-rays are often the first test done, but other imaging tests such as CT scans, MRIs, or bone scans may be used to provide more detailed information about the fracture and the underlying disease.

Treatment

Treatment for a pathologic fracture depends on the cause of the fracture and the patient's overall health. Treatment options may include surgery, radiation therapy, chemotherapy, or bisphosphonates, which are medications that can help strengthen bones. In some cases, a bone graft may be used to help repair the fracture.

Prognosis

The prognosis for a pathologic fracture depends on a variety of factors, including the underlying cause of the fracture, the patient's overall health, and the location and severity of the fracture. In general, pathologic fractures can take longer to heal than normal fractures, and they may require more intensive treatment.

See also

• Bone fracture
• Osteoporosis
• Metastatic bone disease
• Paget's disease of bone

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