Perineurium
Perineurium
Perineurium (pronunciation: per-uh-noor-ee-uhm) is a layer of connective tissue that surrounds a bundle of nerve fibers, known as a fascicle, within a nerve. The perineurium is vital for maintaining the blood-nerve barrier and plays a crucial role in the overall function and health of peripheral nerves.
Etymology
The term "perineurium" is derived from the Greek words "peri," meaning "around," and "neuron," meaning "nerve." Thus, "perineurium" essentially translates to "around the nerve."
Structure
The perineurium is composed of perineurial cells, which are specialized cells that form a protective sheath around the nerve fascicles. These cells are connected by tight junctions, which help to maintain the blood-nerve barrier and prevent the entry of harmful substances into the nerve fibers.
Function
The primary function of the perineurium is to protect the nerve fibers and maintain the blood-nerve barrier. It also helps to regulate the exchange of nutrients and waste products between the nerve fibers and the surrounding blood vessels.
Related Terms
- Fascicle: A bundle of nerve fibers within a nerve.
- Blood-Nerve Barrier: A protective barrier that prevents harmful substances from entering the nerve fibers.
- Peripheral Nerves: The nerves outside the brain and spinal cord.
- Connective Tissue: Tissue that supports, binds, or separates other tissues or organs.
External links
- Medical encyclopedia article on Perineurium
- Wikipedia's article - Perineurium
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