Procyanidin B5
Procyanidin B5 is a type of procyanidin, a class of flavonoids that are widely distributed in the plant kingdom. Procyanidins are known for their potent antioxidant properties and potential health benefits. Procyanidin B5, in particular, has been studied for its potential effects on cardiovascular health, inflammation, and cancer.
Chemical Structure
Procyanidin B5 is a dimeric flavonoid, meaning it consists of two flavonoid units joined together. It is composed of two epicatechin molecules linked through a C4-C8 bond. This type of bond is characteristic of B-type procyanidins, which also include procyanidin B1, procyanidin B2, and others.
Sources
Procyanidin B5 is found in a variety of plant-based foods, including certain types of fruit, nuts, and grains. It is particularly abundant in grape seeds, apple peels, and cocoa.
Health Benefits
Research on procyanidin B5 has suggested several potential health benefits. Its antioxidant properties may help protect cells from damage by free radicals, unstable molecules that can contribute to aging and disease. Some studies have also suggested that procyanidin B5 may have anti-inflammatory effects, potentially helping to reduce the risk of conditions like heart disease and arthritis.
In addition, some research has suggested that procyanidin B5 may have anti-cancer properties. In laboratory studies, it has been shown to inhibit the growth of certain types of cancer cells, although more research is needed to confirm these findings in humans.
Safety and Side Effects
Procyanidin B5 is generally considered safe when consumed as part of a normal diet. However, high doses may cause side effects such as nausea, stomach upset, and diarrhea. As with any supplement, it is important to consult a healthcare provider before starting to take procyanidin B5.
See Also
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Contributors: Prab R. Tumpati, MD