Pseudoacanthosis nigricans
Pseudoacanthosis Nigricans (pronunciation: soo-doh-uh-kan-tho-sis ny-gri-kanz) is a medical condition characterized by dark, velvety discoloration in body folds and creases. The condition is most commonly associated with obesity or other endocrine disorders.
Etymology
The term "Pseudoacanthosis Nigricans" is derived from the Greek words "pseudo" meaning false, "akantha" meaning thorn, and "niger" meaning black. This refers to the appearance of the skin condition, which is often dark and rough, resembling a thorny surface.
Symptoms
The primary symptom of Pseudoacanthosis Nigricans is the presence of dark, velvety skin in body folds and creases. This can occur in various parts of the body, including the neck, armpits, and groin. The skin may also become thickened and may have an odor.
Causes
Pseudoacanthosis Nigricans is most commonly associated with obesity and insulin resistance. It can also be associated with certain endocrine disorders such as polycystic ovary syndrome and Cushing's syndrome. In rare cases, it can be a sign of an underlying cancer.
Treatment
Treatment for Pseudoacanthosis Nigricans primarily involves addressing the underlying condition. This may involve weight loss in cases of obesity, or treatment of the underlying endocrine disorder. Topical treatments such as retinoids, vitamin D analogs, and dermabrasion may also be used to improve the appearance of the skin.
Related Terms
- Acanthosis Nigricans
- Insulin Resistance
- Obesity
- Endocrine Disorder
- Polycystic Ovary Syndrome
- Cushing's Syndrome
- Cancer
External links
- Medical encyclopedia article on Pseudoacanthosis nigricans
- Wikipedia's article - Pseudoacanthosis nigricans
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