Serum sickness
Serum Sickness
Serum sickness (/ˈsɪərəm ˈsɪknɪs/) is a type of hypersensitivity reaction that occurs when the immune system reacts to medications or antibodies that have been injected into the blood stream. The term "serum sickness" is derived from the fact that the condition was first observed in patients who had been injected with horse serum as part of their treatment.
Symptoms
Symptoms of serum sickness can include rash, fever, joint pain, swelling, and sometimes lymph node enlargement. These symptoms usually appear 1 to 2 weeks after exposure to the drug or antibody.
Causes
Serum sickness is caused by the immune system's reaction to certain medications or antibodies. These can include antitoxins, certain antibiotics, and some drugs used to prevent organ transplant rejection.
Treatment
Treatment for serum sickness typically involves discontinuing the medication or antibody that caused the reaction. In some cases, medications such as corticosteroids or antihistamines may be used to help manage symptoms.
See Also
External links
- Medical encyclopedia article on Serum sickness
- Wikipedia's article - Serum sickness
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