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Template:Inflammation

From WikiMD's medical encyclopedia

Inflammation
Symptoms
* Flushing (Rubor)
  • Fever (Calor)
  • Swelling (Tumor)
  • Pain (Dolor)
  • Malaise
Mechanism
Acute
Plasma-derived mediators
* Bradykinin
  • complement
    • C3
    • C5a
    • MAC
  • coagulation
    • Factor XII
    • Plasmin
    • Thrombin
Cell-derived mediators
preformed:
* Lysosome granules
  • biogenic amines
    • Histamine
    • Serotonin
synthesized on demand:
* cytokines
    • IFN-γ
    • IL-8
    • TNF-α
    • IL-1
  • eicosanoids
    • Leukotriene B4
    • Prostaglandins
  • Nitric oxide
  • Kinins
Chronic
* Macrophage
  • Epithelioid cell
  • Giant cell
  • Granuloma
Other
* Acute-phase reaction
  • Vasodilation
  • Increased vascular permeability
  • Exudate
  • Leukocyte extravasation
  • Chemotaxis
Tests
* Full blood count
    • Leukocytosis
  • C-reactive protein
  • Erythrocyte sedimentation rate
General
* Lymphadenopathy
  • List of inflammed body part states


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