Bekanamycin
Bekanamycin (pronounced: be-ka-na-my-cin) is an aminoglycoside antibiotic that is used in the treatment of various types of bacterial infections. It is also known by the trade name Kanendomycin.
Etymology
The term "Bekanamycin" is derived from the Japanese word "Bekana", which means "small leek", and "mycin", a common suffix for antibiotics derived from Streptomyces bacteria. The name was given by the Japanese scientists who first isolated the compound from the soil bacterium Streptomyces kanamyceticus.
Pharmacology
Bekanamycin works by binding to the 30S ribosomal subunit of the bacteria, inhibiting protein synthesis and leading to cell death. It is effective against both Gram-positive and Gram-negative bacteria.
Clinical Use
Bekanamycin is used to treat a variety of bacterial infections, including tuberculosis, pneumonia, and sepsis. It is also used in combination with other antibiotics to treat multi-drug resistant infections.
Side Effects
Like other aminoglycosides, Bekanamycin can cause ototoxicity and nephrotoxicity. Other side effects may include allergic reactions, nausea, and vomiting.
Related Terms
- Aminoglycoside
- Antibiotic
- Bacterial Infections
- 30S Ribosomal Subunit
- Gram-positive bacteria
- Gram-negative bacteria
- Tuberculosis
- Pneumonia
- Sepsis
- Ototoxicity
- Nephrotoxicity
External links
- Medical encyclopedia article on Bekanamycin
- Wikipedia's article - Bekanamycin
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