Adipokines
Adipokines
Adipokines (pronounced: ad-i-po-kines) are a type of protein that is secreted by adipose tissue. They play a crucial role in the regulation of various metabolic processes, including glucose regulation and fatty acid catabolism.
Etymology
The term "Adipokines" is derived from "adipo-" meaning fat and "-kines" from cytokines, which are proteins that are important in cell signaling.
Function
Adipokines are primarily produced in adipose tissue, but they can also be produced by other tissues, including muscle and liver. They are involved in a wide range of physiological processes, such as energy metabolism, inflammation, and insulin resistance. Some of the most well-known adipokines include leptin, adiponectin, resistin, and visfatin.
Clinical Significance
Adipokines are of significant interest in medicine due to their role in various diseases, including obesity, diabetes, cardiovascular disease, and cancer. For example, abnormal levels of adipokines are often found in individuals with obesity, which can lead to insulin resistance and increase the risk of developing type 2 diabetes and cardiovascular disease.
Related Terms
- Leptin: A hormone that regulates food intake and energy expenditure.
- Adiponectin: A protein hormone that modulates a number of metabolic processes, including glucose regulation and fatty acid oxidation.
- Resistin: A hormone that is believed to play a role in obesity and insulin resistance.
- Visfatin: A protein that is thought to play a role in metabolism and aging.
External links
- Medical encyclopedia article on Adipokines
- Wikipedia's article - Adipokines
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