Aliskiren/amlodipine
Aliskiren/Amlodipine
Aliskiren/Amlodipine (pronunciation: al-is-KYE-ren/am-LOE-di-peen) is a combination medication used in the treatment of high blood pressure (hypertension).
Etymology
The name Aliskiren is derived from the chemical name (2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2-methylpropyl)-4-hydroxy-2-isopropyl-7-[[(2R,4S,6S)-4-methyl-6-(methylamino)-3,4-dihydro-2H-pyran-2-yl]oxy]-8,8-dimethyl-, (2S,3R,4R,5S,6R)-2-[(2R,3R,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol.
Amlodipine is derived from the chemical name 3-Ethyl 5-methyl (4RS)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate.
Usage
Aliskiren is a renin inhibitor, which works by decreasing substances in the body that narrow blood vessels and raise blood pressure. Amlodipine is a calcium channel blocker, which relaxes the blood vessels, improving blood flow and making it easier for the heart to pump.
Related Terms
Side Effects
Common side effects of Aliskiren/Amlodipine include dizziness, lightheadedness, swelling ankles/feet, or flushing. Serious side effects include fainting, fast/irregular/pounding heartbeat, and symptoms of a high potassium blood level (such as muscle weakness, slow/irregular heartbeat).
Precautions
Before taking Aliskiren/Amlodipine, inform your doctor or pharmacist if you are allergic to either aliskiren or amlodipine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
External links
- Medical encyclopedia article on Aliskiren/amlodipine
- Wikipedia's article - Aliskiren/amlodipine
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