Micafungin

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Micafungin (pronounced: my-ca-fun-gin) is an antifungal medication used to treat and prevent fungal infections. It is a member of the echinocandin class of antifungal drugs and works by inhibiting the synthesis of beta-1,3-glucan, an essential component of fungal cell walls.

Etymology

The name "Micafungin" is derived from the generic name "Mica" and "fungin", indicating its antifungal properties.

Usage

Micafungin is used to treat a variety of fungal infections, particularly those caused by the Candida species. It is also used as a prophylactic in patients undergoing hematopoietic stem cell transplantation to prevent fungal infections.

Mechanism of Action

Micafungin works by inhibiting the enzyme 1,3-beta-D-glucan synthase, thereby preventing the synthesis of beta-1,3-glucan, a crucial component of the fungal cell wall. This leads to osmotic instability and ultimately the death of the fungus.

Side Effects

Common side effects of Micafungin include nausea, vomiting, diarrhea, rash, and fever. In rare cases, it can cause serious side effects such as anaphylaxis, hepatotoxicity, and hemolysis.

Related Terms

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External links

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