Belatacept

Belatacept

Belatacept (pronounced as bel-uh-TAS-ept) is a type of immunosuppressive drug used in organ transplantation, specifically for kidney transplant patients. It is marketed under the brand name Nulojix.

Etymology

The name "Belatacept" is derived from its chemical structure. The prefix "bela-" is an abbreviation of the chemical name, while "-cept" is a common suffix for receptor modulators.

Usage

Belatacept is used to prevent organ rejection in patients who have received a kidney transplant. It works by blocking the action of certain cells in the immune system that can cause the body to reject the transplanted organ.

Mechanism of Action

Belatacept works by binding to a protein called CD80 and CD86 on the surface of certain immune cells. This prevents these cells from activating a type of immune cell called a T cell, which can attack the transplanted organ.

Side Effects

Common side effects of Belatacept include anemia, diarrhea, urinary tract infection, and peripheral edema. Serious side effects can include progressive multifocal leukoencephalopathy, a rare brain infection that can be fatal.

Related Terms

• Immunosuppressive drug
• Organ transplantation
• Kidney transplant
• Organ rejection
• CD80
• CD86
• Anemia
• Diarrhea
• Urinary tract infection
• Peripheral edema
• Progressive multifocal leukoencephalopathy

External links

• Medical encyclopedia article on Belatacept
• Wikipedia's article - Belatacept

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