Tofacitinib

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Tofacitinib

Tofacitinib (pronounced toh-fa-si-ti-nib) is a medication used in the treatment of rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It is classified as a Janus kinase inhibitor, which works by blocking the action of Janus kinases, enzymes that play a key role in the inflammatory process.

Etymology

The name "Tofacitinib" is derived from the compound's chemical structure. The "Tofa" part of the name is an abbreviation of the chemical group to which the drug belongs, while "citinib" is a common suffix used for drugs that inhibit certain enzymes.

Usage

Tofacitinib is used to treat moderate to severe forms of rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis when other treatments have not worked or cannot be used. It is taken orally, usually twice a day.

Side Effects

Common side effects of Tofacitinib include diarrhea, headache, and upper respiratory tract infection. Serious side effects may include infections, cancer, and blood clots.

Related Terms

  • Rheumatoid arthritis: A chronic inflammatory disorder affecting many joints, including those in the hands and feet.
  • Psoriatic arthritis: A form of arthritis that affects some people who have psoriasis.
  • Ulcerative colitis: A chronic, inflammatory bowel disease that causes inflammation in the digestive tract.
  • Janus kinase inhibitor: A type of drug that blocks the action of Janus kinases, enzymes that play a key role in the inflammatory process.

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