TNF inhibitor
TNF inhibitor
TNF inhibitors (pronunciation: /tɪˈɛnɛf ɪnˈhɪbɪtər/) are a type of pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the immune system and plays a role in inflammation. TNF inhibitors are used in the treatment of autoimmune diseases such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease.
Etymology
The term "TNF inhibitor" is derived from the name of the substance they inhibit, "tumor necrosis factor". The word "inhibitor" comes from the Latin word "inhibere", which means "to hold back".
Mechanism of action
TNF inhibitors work by neutralizing the tumor necrosis factor alpha (TNFα), a cytokine that plays a pivotal role in inflammatory responses. By blocking the action of TNFα, these drugs reduce inflammation and halt the progression of the disease.
Types of TNF inhibitors
There are several types of TNF inhibitors, including:
Each of these drugs works in a slightly different way to inhibit TNF.
Side effects
Like all drugs, TNF inhibitors can have side effects. These can include infections, allergic reactions, and in rare cases, lymphoma.
Related terms
External links
- Medical encyclopedia article on TNF inhibitor
- Wikipedia's article - TNF inhibitor
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