Goserelin
Goserelin (pronounced goh-SEH-reh-lin) is a synthetic decapeptide analogue of gonadotropin-releasing hormone (GnRH) with potent antagonist properties. It is primarily used in the treatment of hormone-responsive cancers such as prostate cancer and breast cancer, and certain menstrual disorders.
Etymology
The term "Goserelin" is derived from its chemical structure, which is a modification of the natural hormone GnRH. The prefix "Gos" is an abbreviation of "Gonadotropin", referring to the hormone that it mimics, and "relin" is a common suffix used in drug nomenclature to denote releasing factors.
Pharmacology
Goserelin works by acting on the pituitary gland in the brain to decrease the production of certain hormones. In men, it reduces the amount of testosterone produced by the body. In women, it reduces the amount of estrogen produced by the body. This can slow or stop the growth of certain types of cancer cells that need these hormones to grow.
Related Terms
- Gonadotropin-releasing hormone (GnRH)
- Antagonist
- Prostate cancer
- Breast cancer
- Menstrual disorders
- Pituitary gland
- Testosterone
- Estrogen
See Also
External links
- Medical encyclopedia article on Goserelin
- Wikipedia's article - Goserelin
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