Propofol
Propofol
Propofol (pronounced proh-POH-fahl) is a short-acting, intravenously administered hypnotic/amnestic agent. Its uses include the induction and maintenance of general anesthesia, sedation for mechanically ventilated adults, and procedural sedation.
Etymology
The name "Propofol" is derived from its chemical name 2,6-diisopropylphenol.
Uses
Propofol is used in a variety of medical procedures, including:
- General anesthesia: Propofol is commonly used to induce and maintain anesthesia during surgery. It is often used in combination with other medications to enhance its effects.
- Sedation: In intensive care units, propofol is used to sedate patients who are on mechanical ventilation.
- Procedural sedation: Propofol can be used for sedation in procedures that do not require general anesthesia, such as colonoscopies or minor surgical procedures.
Pharmacology
Propofol works by increasing the activity of the neurotransmitter GABA, which inhibits activity in the brain. This results in a decrease in consciousness and a lack of response to stimuli.
Side Effects
Common side effects of propofol include:
- Hypotension: Propofol can cause a drop in blood pressure, which can be dangerous in certain patients.
- Respiratory depression: Propofol can slow or stop breathing, which is why it is often used in conjunction with mechanical ventilation.
- Nausea and vomiting: These are common side effects of many anesthetics, including propofol.
Related Terms
External links
- Medical encyclopedia article on Propofol
- Wikipedia's article - Propofol
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