Tasimelteon
Tasimelteon
Tasimelteon (pronounced ta-si-mel-te-on) is a drug used for the treatment of non-24-hour sleep–wake disorder (non-24). It is a selective agonist for the melatonin receptors MT1 and MT2 in the suprachiasmatic nucleus of the brain, the same receptors most directly involved in the sleep-wake cycle.
Etymology
The name "Tasimelteon" is derived from a combination of parts of the words "tasis" and "melatonin". "Tasis" is a Greek word meaning "arrangement" or "order", and "melatonin" is the hormone that regulates the sleep-wake cycle. The name thus suggests the drug's function of helping to regulate the sleep-wake cycle.
Usage
Tasimelteon is used to treat non-24-hour sleep–wake disorder, a chronic circadian rhythm sleep disorder that is common among the totally blind. It is taken orally, usually before bedtime.
Side Effects
Common side effects of Tasimelteon include headache, elevated liver enzymes, nightmares or unusual dreams, upper respiratory or urinary tract infection. If any of these effects persist or worsen, the patient should notify their doctor or pharmacist promptly.
Related Terms
- Melatonin receptor
- Suprachiasmatic nucleus
- Non-24-hour sleep–wake disorder
- Circadian rhythm sleep disorder
External links
- Medical encyclopedia article on Tasimelteon
- Wikipedia's article - Tasimelteon
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