Low-Density Lipoprotein (LDL)

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Low-Density Lipoprotein (LDL) is a type of protein that transports LDL or the so called “bad” cholesterol in the blood.

What is the significance?[edit]

LDL is the major cholesterol carrier in the blood.

Also see[edit]

LDL cholesterol

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Lipids: lipoprotein particle metabolism

Lipoprotein particle classes and subclasses	* delivery of TGs: Chylomicron VLDL delivery of C and CE: IDL LDL lb LDL sd LDL Lp(a) HDL Remnant cholesterol
Apolipoproteins	* APOA 1 2 4 5 APOB APOC 1 2 3 4 APOD APOE APOH SAA SAA1
Extracellular enzymes	* LCAT LIPC LPL
Lipid transfer proteins	* CETP MTTP PLTP
Cell surface receptors	* HDL: SCARB1 IDL: LRP LRP1 LRP1B LRP2 LRP3 LRP4 LRP5 LRP5L LRP6 LRP8 LRP10 LRP11 LRP12 LDL: LDLR LRPAP1

Cardiovascular disease (vessels)

Arteries, arterioles
and capillaries

Peripheral artery disease

Arteriosclerosis	* Atherosclerosis Foam cell Fatty streak Atheroma Intermittent claudication Critical limb ischemia Monckeberg's arteriosclerosis Arteriolosclerosis Hyaline Hyperplastic Cholesterol LDL Oxycholesterol Trans fat
Stenosis	* Carotid artery stenosis Renal artery stenosis
Other	* Aortoiliac occlusive disease Degos disease Erythromelalgia Fibromuscular dysplasia Raynaud's phenomenon

Aneurysm / dissection /
pseudoaneurysm

* torso: Aortic aneurysm

Vascular malformation

* Arteriovenous fistula

* Cherry hemangioma

Inflammation	* Phlebitis
Venous thrombosis / Thrombophlebitis	* primarily lower limb Deep vein thrombosis abdomen Hepatic veno-occlusive disease Budd–Chiari syndrome May–Thurner syndrome Portal vein thrombosis Renal vein thrombosis upper limb / torso Mondor's disease Paget–Schroetter disease head Cerebral venous sinus thrombosis Post-thrombotic syndrome
Varicose veins	* Gastric varices Portacaval anastomosis Caput medusae Esophageal varices Hemorrhoid Varicocele
Other	* Chronic venous insufficiency Chronic cerebrospinal venous insufficiency Superior vena cava syndrome Inferior vena cava syndrome Venous ulcer

Arteries or veins

Hypertension	* Hypertensive heart disease Hypertensive emergency Hypertensive nephropathy Essential hypertension Secondary hypertension Renovascular hypertension Benign hypertension Pulmonary hypertension Systolic hypertension White coat hypertension
Hypotension	* Orthostatic hypotension

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