Yescarta

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Yescarta
TermYescarta
Short definitionYescarta - (pronounced) (yes-KAR-tuh) drug used to treat adults with follicular lymphoma or certain types of large B-cell lymphoma that has relapsed (returned) or failed to improve after treatment with at least two other systemic therapies. It is also being studied in the treatment of other types of cancer. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


Yescarta - (pronounced) (yes-KAR-tuh) drug used to treat adults with follicular lymphoma or certain types of large B-cell lymphoma that has relapsed (returned) or failed to improve after treatment with at least two other systemic therapies. It is also being studied in the treatment of other types of cancer. Yescarta is made using a patient's T cells (a type of cell in the immune system). A gene for a special receptor called the chimeric antigen receptor (CAR) is added to the T cells in the laboratory. Large numbers of these modified T cells, known as CAR T cells, are cultivated in the laboratory and given to the patient by infusion. Yescarta attaches to a protein called CD19, which is found on most B-cell lymphoma cells. This helps the body's immune system kill cancer cells. Yescarta is a form of CAR T cell therapy. Also called axicabtagene ciloleucel

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